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In this commentary, the author describes the activities and the rationale of the Department of Science Teaching at the Weizmann Institute of Science. This department was active over a long period of time. She writes that the holistic approach of connecting science disciplines to teaching and learning of the sciences in the educational system in Israel is commendable. This approach includes all the components that characterize science curricula: development, implementation to include intensive and comprehensive long term professional development of science and mathematics teachers, research and assessment. It has become a leading example of a multifaceted endeavor encompassing the creation of learning materials, preparation of teachers, and conduct of research on teaching and learning.