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In recent decades, Venezuela has faced a severe economic and social crisis, precipitated by political instability, which in turn has particularly affected public health provision. Here, we assess how Venezuela’s health crisis has impacted mosquito-borne infectious diseases (MBID s), placing Venezuela as the hotspot of malaria in the region and one of the countries currently reporting yellow fever outbreaks in the Americas. We describe the reshaping of the MBID epidemiological landscape in the midst of a changing environmental setting, highlighting the main knowledge gaps. The rise of MBID in Venezuela has the potential to severely undermine regional disease elimination efforts. Therefore, national, and regional measures must be taken to address these worsening epidemics and prevent their spread beyond country borders.
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