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In the last two and half decades, Plato’s Timaeus has reawakened the interest of scholars, resulting in extensive research into the influence of this work on a wide range of intellectual traditions and cultural production since antiquity. This introduction considers the unexplored reasons for this influence of the Timaeus in shaping and conditioning the multidisciplinary worlds of learning in ancient, medieval, and Renaissance Europe. In a general assessment of the influence on Plato’s successors of the text and its offshoots, we investigate why and how the mathematical principles of the Timaean creation myth came to function as a scientific language in multifarious technical disciplines, how the dialogue was used to reconcile ancient Greek philosophy and science with Christian and Islamic beliefs, to what extent its view on the cosmos influenced various conceptions of human nature, and how far the text with its mathematical approaches which gave rise to the four mathematical disciplines of the quadrivium – arithmetic, music, geometry, and astronomy – came to underpin emergent practices in natural philosophy, music, medicine, and architecture. We argue that the Timaeus’ combination of a high degree of complexity, incompleteness, vagueness, and even obscurity did not discourage its ancient, medieval, and Renaissance readers, but, rather, was seen as a challenge to reveal its secrets and to formulate creative interpretations that professed to make sense of its contents.
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