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Regina Salomea Pilsztyn, doctoress of medicine and ophthalmologist, is the authoress of a diary in Polish, characteristically entitled The practice of journey and my life’s adventures. An outcast in Poland because of her independence, excessive enterprise, eloquence, education, but also her inadequate fulfilment of the role of mother and wife, she found her place on earth far away from her homeland, in the world of Islam. In Turkey, she was primarily a stranger, but she was accepted by the culturally different community. Regina Salomea’s diary, unpublished until the 20th century, is an interesting itinerary abounding in rich cultural observations and comments.