The description of individual teeth, the dentition as a whole, and the main features of tooth-bearing bones in Ophisaurus apodus is given. The tooth replacement is rather different from that described for non-mammalian vertebrates (the wave replacement of alternate teeth). The wave of replacement affects adjacent teeth, not even and odd teeth separately. In some periods of the life none of the teeth are replaced which suggests that replacement is not continuous in time. As a result the posterior set of teeth becomes permanent and much worn in aged specimens.