This paper surveys the relationship between Clergy Vocational Conflict, cognitive conflict (religious conflict and Quest) and psychological well-being in a sample of 178 Muslim clergy in Turkey. It was found that Clergy Vocational Conflict is accompanied by religious conflict and Quest. Those who experienced Clergy Vocational Conflict and religious conflict (but not Quest) suffered from poor psychological well-being. Quest, which does not affect psychological well-being, and religious conflict, which adversely affects it, are more common among the younger stratum of the sample. However, well-being prevails among the older layer and among the more educated clergy. Finally, psychological well-being, self-esteem, Quest and religious conflict were found as predictors for Clergy Vocational Conflict.