Promoting Chinese Herbal Drugs through Regulatory Globalisation

The Case of the Consortium for Globalization of Chinese Medicine

in Asian Medicine
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This study explores the social dynamics in promoting traditional Chinese medicine (tcm) drugs by making them acceptable to biomedical markets. It investigates the Consortium for Globalization of Chinese Medicine (cgcm), an organisation based in Hong Kong in pursuit of advancing tcm, and traces the development of the herbal formula phy906, a Chinese herbal product intensively discussed at the cgcm that has been tested according to the us Food and Drug Administration’s regulation for approval. Departing from accounts on the organisation’s success that focus either on its scientific approach or its leader Yung-chi Cheng, this paper argues that it was the synergy between the cgcm and the pursuit of approval for phy906 that contributed to the regulatory globalisation of tcm. In this process, not only organisations like the cgcm are required to streamline efforts for producing globalised tcm; also researchers are needed who, with cultural commitment, seek for transforming tcm to meet biomedical indications.

Asian Medicine

Journal of the International Association for the Study of Traditional Asian Medicine

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References

bcc Research ‘Botanical and Plant-Derived Drugs: Global Markets’ 2015 last accessed on 2 March 2016 (Report highlights). url: <http://www.bccresearch.com/market-research/biotechnology/botanical-plant-derived-drugs-report-bio022g.html>

ChenS. T.DouJ.TempleR.AgarwalR.WuK. M.WalkerS. ‘New Therapies from Old Medicines’ Nature Biotechnology 2008 16 10 1077 1083

ChengY. C.LiuS. H. ‘Composition Consisting of phy906 and Chemotherapeutic Agents’ 2001 us Patent issue number: wo 2001066123 A2

China News Service ‘Conversations between Chief Executive Chee-hwa Tung and Legislative Council Members’ China.org.cn 2001 last accessed on 30 October 2014 url: <http://big5.china.com.cn/chinese/TCC/65845.htm>

FarrellM. P.KummarS. ‘Phase i/iia Randomized Study of phy906, a Novel Herbal Agent, as a Modulator of Chemotherapy in Patients with Advanced Colorectal Cancer’ Clinical Colorectal Cancer 2003 2 253 256

FischerM. M. J. GoodB. J.FischerM. M. J.WillenS. S.DelVecchio GoodM.-J. ‘Dr Judah Folkman’s Decalogue and Network Analysis’ A Reader in Medical Anthropology: Theoretical Trajectories, Emergent Realities 2012 Chichester Wiley-Blackwell 339 344

FurthC. ‘The AMS/Paterson Lecture: Becoming Alternative? Modern Transformations of Chinese Medicine in China and in the United States’ Canadian Bulletin of Medical History/Bulletin canadien d’histoire de la medicine 2011 28 1 5 41

HansonM. ‘Is the 2015 Nobel Prize a Turning Point for Traditional Chinese Medicine?’ The Conversation 2015 last accessed on 2 March 2016 (6 October 2015), url: <http://theconversation.com/is-the-2015-nobel-prize-a-turning-point-for-traditional-chinese-medicine-48643>

JasanoffS. JasanoffS. ‘The Idiom of Co-Production’ States of Knowledge: The Co-Production of Science and the Social Order 2004 London and New York Routledge 6 12

JasanoffS. CamicC.GrossN.LamontM. ‘The Practices of Objectivity in Regulatory Science’ Social Knowledge in the Making 2011 Chicago University of Chicago Press 307 337

KuoW. H. ‘Bridging Studies in Japan and Taiwan: A Dynamic Evolution in Regulating Ethnic Differences’ Drug Information Journal (sci) 2009 43 3 10

LamW.LiuS.-H.JiangZ.ChengY.-C. ‘Lessons from the Development of the Traditional Chinese Medicine Formula phy906’ Science 2015 347 6219 S43 S44

LiuS. H.ChengY. C. ‘Old Formula, New Rx: The Journey of phy906 as Cancer Adjuvant Therapy’ Journal of Ethnopharmacology 2012 140 3 614 623

LiuS. H.JiangZ.ChengY. C. ‘A Chinese Medicine Formulation, phy906 Can Enhance the Therapeutic Index of CPT-Il and Other Anticancer Drugs against Cancer in Mice’ American Association for Cancer Research 2001 41 458

LiuS. H.JiangZ.ChengY. C. ‘Botanical Activity Relationship in Traditional Chinese Medicine: Studies of phy906 as an Adjuvant Therapy with Cancer Chemotherapeutic Agents’ Proceedings of American Association for Cancer Research 2002 43 4758

LiuS. H.JiangZ.LiddilJ. ‘Prevention of CPT-Il Induced Toxicity by a Chinese Medicinal Formulation, phy-906’ American Association for Cancer Research 2000 41 2608

LockM. LockM.NguyenV. K. ‘Anthropologies of Medicine’ An Anthropology of Biomedicine 2010 London Wiley-Blackwell 57 82

PordiéL.GaudillièreJ. P. ‘The Reformulation Regime in Drug Discovery: Revisiting Polyherbals and Property Rights in the Ayurvedic Industry’ East Asian Science, Technology and Society: An International Journal 2014 8 1 1 23

SaifM. W.LansiganF.RutaS.LambL.MezesM.ElligersK.GrantN.JiangZ.LiuS. H.ChengY. C. ‘Phase I Study of the Botanical Formulation phy906 with Capecitabine in Advanced Pancreatic and Other Gastrointestinal Malignancies’ Phytomedicine 2010a 17 161 169

SaifM. W.LiJ.LambL.KaleyK.BussomS.CarboneR.ElligersK.KrishnamoorthyS.LiuS. H.ChengY. C. ‘Phase II Study of phy906 plus Capecitabine (CAP) in PTS with Gemcitabine-Refractory Pancreatic Cancer (PC) and Measurement of Cytokines’ Journal of Clinical Oncology 2010b 28 e14540 (supplement abstract)

SaifM. W.LiJ.LambL.KaleyK.ElligersK.JiangZ.BussomS.LiuS. H.ChengY. C. ‘First-in-human Phase II Trial of the Botanical Formulation phy906 with Capecitabine as Second-line Therapy in Patients with Advanced Pancreatic Cancer’ Cancer Chemotherapy Pharmacology 2014 73 2 373 380

TengC. M.(鄧哲明) ‘Review and Prospects of Taiwan’s tcm research’ [台灣中草藥研究回顧與展望] 2014 last accessed on 11 August 2015 lecture at Graduate Institute of Natural Products, Kaohsiung Medical University, 27 September 2014 (presentation slide), url: <http://nphs.kmu.edu.tw/index.php/zh-TW/公告事項/活動公告/78-台灣中草藥研究回顧與展望-鄧哲明教授主講. ppt slides

United States Food and Drug Administration (fda) ‘Guidance for Industry: Botanical Drug Products’ 2004 last accessed on 11 August 2012 url: <http://www.fda.gov/downloads/drugs/guidancecomplianceregulatoryinformation/guidances/ucm070491.pdf>

YinS. Y.WeiW. C.JianF. Y.YangN. S. ‘Therapeutic Applications of Herbal Medicines for Cancer Patients’ Evidence-Based Complementary and Alternative Medicine 2013 last accessed on 2 March 2016 Volume 2013 Article id 302426, url: <http://dx.doi.org/10.1155/2013/302426>

ZhanM. Other-Worldly: Making Chinese Medicine through Transnational Frames 2009 Durham, NC Duke University Press

ZhangX.-C.(张学全)ShenJ.(盛骏) ‘The First Three Steps to Turn tcm into Scientific Prescription’ [中药要变成科学处方必须走好头三步] 2004 last accessed on 19 November 2014 Report at www.med66.com, 25 July 25 2004. url: <http://www.med66.com/html/ziliao/07/64/055b16101a3381e4f963bdb30117593a.htm>

1

Furth 2011, p. 5.

2

Zhan 2009.

3

Hanson 2015.

8

Lock 2010, p. 59.

9

Pordié and Gaudillière 2014.

11

Lam, Liu, Jiang, and Cheng 2015.

12

Jasanoff 2004.

17

Chen et al. 2008.

18

Teng 2014.

23

China News Service 2001.

33

Pordié and Gaudillière 2014.

34

Yin et al. 2013.

37

Pordié and Gaudillière 2014, p. 7.

40

Papers include Liu, Jiang, Liddil et al. 2000, Liu, Jiang, and Cheng 2001, and Liu, Jiang, and Cheng 2002.

41

Cheng and Liu 2001.

43

Liu and Cheng 2012.

44

Farrell and Kummar 2003.

47

Saif et al. 2010a, 2010b, and 2014.

49

Liu and Cheng 2012, p. 621.

52

Zhang and Shen 2004.

56

As noted in the 5th meeting, in 2006, there were already seven regions, including Taiwan, Hong Kong, Beijing, Shanghai, Guangdong/Guangzhou (广东/广州), Australia/South Pacific, and Canada. Although the definition of these regions is arbitrary, according to the official website of cgcm, there are 11 local chapters. In addition to those mentioned above, they are uk, Europe, Korea, and Chongqing (重庆).

61

Jasanoff 2011.

62

Ibid., p. 308.

63

Fischer 2012.

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