Interactions between social behaviour and the acute phase immune response in house finches

in Behaviour
Restricted Access
Get Access to Full Text
Rent on DeepDyve

Have an Access Token?



Enter your access token to activate and access content online.

Please login and go to your personal user account to enter your access token.



Help

Have Institutional Access?



Access content through your institution. Any other coaching guidance?



Connect

In social organisms, immune-mediated behavioural changes (sickness behaviours) can both influence and respond to social dynamics. We tested whether social status in house finches (Haemorhous mexicanus) modulates the acute phase response or aggressive interactions with flockmates. We treated subordinate or dominant finches within captive flocks with lipopolysaccharide (LPS) to stimulate an acute phase response (APR), and quantified mass loss, activity, foraging behaviours, and agonistic interactions. Subordinate finches lost more mass than dominants in response to LPS, but social status did not influence the expression of sickness behaviours (activity and foraging) upon LPS injection. LPS-injected subordinate birds experienced reduced aggression from mid-ranking but not dominant flockmates, indicating status-mediated effects of sickness behaviour on agonistic interactions. Our results suggest that social status in house finches influences one component of the APR (mass loss) and can interact with the APR to modulate intraspecific agonistic interactions in ways likely relevant for disease transmission.

Interactions between social behaviour and the acute phase immune response in house finches

in Behaviour

Sections

References

AdelmanJ.S.MartinL.B. (2009). Vertebrate sickness behaviors: adaptive and integrated neuroendocrine immune responses. — Integr. Comp. Biol. 49: 202-214.

AdelmanJ.S.Córdoba-CórdobaS.SpoelstraK.WikelskiM.HauM. (2010). Radiotelemetry reveals variation in fever and sickness behaviours with latitude in a free-living passerine. — Funct. Ecol. 24: 813-823.

AdelmanJ.S.CarterA.W.HopkinsW.A.HawleyD.M. (2013). Deposition of pathogenic Mycoplasma gallisepticum onto bird feeders: host pathology is more important than temperature-driven increases in food intake. — Biol. Lett. 9: 20130594.

AdelmanJ.S.MoyersS.C.FarineD.R.HawleyD.M. (in press). Feeder use predicts both acquisition and transmission of a contagious pathogen in a North American songbird. — Proc. Roy. Soc. Lond. B: Biol. Sci.

AltizerS.HochachkaW.M.DhondtA.A. (2004). Seasonal dynamics of mycoplasmal conjunctivitis in eastern North American house finches. — J. Anim. Ecol. 73: 309-322.

AubertA.GoodallG.DantzerR.GheusiG. (1997). Differential effects of lipopolysaccharide on pup retrieving and nest building in lactating mice. — Brain Behav. Immunol. 11: 107-118.

BlumsteinD.T.EvansC.S.DanielJ.C. (2000). JWatcher™ 0.9. An introductory user’s guide. — Animal Behavioral Laboratory, Macquarie UniversitySydney, NSW. Available online at http://www.jwatcher.ucla.edu/JWmanual.pdf.

BouwmanK.M.HawleyD.M. (2010). Sickness behaviour acting as an evolutionary trap? Male house finches preferentially feed near diseased conspecifics. — Biol. Lett. 6: 462-465.

CohnD.W.H.de Sá-RochaL.C. (2006). Differential effects of lipopolysaccharide in the social behavior of dominant and submissive mice. — Physiol. Behav. 87: 932-937.

CohnD.W.H.de Sá-RochaL.C. (2009). Sickness and aggressive behavior in dominant and subordinate mice. — Ethology 115: 112-121.

DantzerR.KelleyK.W. (2007). Twenty years of research on cytokine-induced sickness behavior. — Brain Behav. Immunol. 21: 153-160.

DhondtA.A.DhondtK.V.HawleyD.M.JennelleC.S. (2007). Experimental evidence for transmission of Mycoplasma gallisepticum in house finches by fomites. — Avian Pathol. 36: 205-208.

DizneyL.DearingM.D. (2013). The role of behavioural heterogeneity on infection patterns: implications for pathogen transmission. — Anim. Behav. 86: 911-916.

FairbanksB.M.HawleyD.M. (2012). Interactions between host social behavior, physiology, and disease susceptibility: the role of dominance status and social context. — In: Ecoimmunology ( DumasG.NelsonR. eds). Oxford University PressNew York, NY p.  440-467.

HartB.L. (1988). Biological basis of the behavior of sick animals. — Neurosci. Biobehav. Rev. 12: 123-137.

HawleyD.M. (2006). Asymmetric effects of experimental manipulations of social status on individual immune response. — Anim. Behav. 71: 1431-1438.

HawleyD.M.AltizerS.M. (2011). Disease ecology meets ecological immunology: understanding the links between organismal immunity and infection dynamics in natural populations. — Funct. Ecol. 25: 48-60.

HawleyD.M.JennelleC.S.SydenstrickerK.V.DhondtA.A. (2007). Pathogen resistance and immunocompetence covary with social status in house finches (Carpodacus mexicanus). — Funct. Ecol. 21: 520-527.

HennessyM.B.DeakT.SchimlP.A. (2014). Sociality and sickness: have cytokines evolved to serve social functions beyond times of pathogen exposure?Brain Behav. Immunol. 37: 15-20.

KleinS.L. (2003). Parasite manipulation of the proximate mechanisms that mediate social behavior in vertebrates. — Physiol. Behav. 79: 441-449.

KolliasG.V.SydenstrickerK.V.KolliasH.W.LeyD.H.HosseiniP.R.ConnollyV.DhondtA.A. (2004). Experimental infection of house finches with Mycoplasma gallisepticum. — J. Wildl. Dis. 40: 79-86.

LopesP.C. (2014). When is it socially acceptable to feel sick?Proc. Roy. Soc. Lond. B: Biol. Sci. 281: 20140218.

LopesP.C.AdelmanJ.WingfieldJ.C.BentleyG.E. (2012). Social context modulates sickness behavior. — Behav. Ecol. Sociobiol. 66: 1421-1428.

LopesP.C.SpringthorpeD.BentleyG.E. (2014). Increased activity correlates with reduced ability to mount immune defenses to endotoxin in zebra finches. — J. Exp. Zool. 321: 422-431.

MooreJ. (2002). Parasites and the behavior of animals. — Oxford University PressOxford.

Owen-AshleyN.T.WingfieldJ.C. (2006). Seasonal modulation of sickness behavior in free-living northwestern song sparrows (Melospiza melodia morphna). — J. Exp. Biol. 209: 3062-3070.

Owen-AshleyN.T.WingfieldJ.C. (2007). Acute phase responses of passerine birds: characterization and seasonal variation. — J. Ornithol. 148: 583-591. DOI:10.1007/s10336-007-0197-2.

Owen-AshleyN.T.TurnerM.HahnT.P.WingfieldJ.C. (2006). Hormonal, behavioral, and thermoregulatory responses to bacterial lipopolysaccharide in captive and free-living white-crowned sparrows (Zonotrichia leucophrys gambelii). — Horm. Behav. 49: 15-29.

RenaultJ.GheusiG.AubertA. (2008). Changes in social exploration of a lipopolysaccharides-treated conspecific in mice: role of environmental cues. — Brain Behav. Immunol. 22: 1201-1207.

ThompsonW.L. (1960a). Agonistic behavior in the house finch. Part I: annual cycle and display patterns. — Condor 62: 245-271.

ThompsonW.L. (1960b). Agonistic behavior in the house finch. Part II: factors in aggressiveness and sociality. — Condor 62: 378-402.

YeeJ.R.PrendergastB.J. (2010). Sex-specific social regulation of inflammatory responses and sickness behaviors. — Brain Behav. Immunol. 24: 942-951.

ZylberbergM.KlasingK.C.HahnT.P. (2013). House finches (Carpodacus mexicanus) balance investment in behavioural and immunological defences against pathogens. — Biol. Lett. 9: 20120856.

Figures

  • View in gallery

    Predicted means and standard errors of changes in mass (g) upon LPS or control injection for dominant and subordinate house finches. Changes were calculated by subtracting pre-injection values from post-injection values. Subordinate birds lost more mass than dominant birds in response to LPS injection (p=0.022).

  • View in gallery

    (a) Predicted means and standard errors of activity (PC1) upon LPS injection versus control injection for dominant and subordinate house finches. Both dominant and subordinate individuals showed a significant reduction in activity when injected with LPS (p<0.001), but activity levels were not influenced by social status. (b) Predicted means and standard errors of changes in foraging behaviour (PC2) upon LPS or control injection for dominant and subordinate house finches. Foraging activities were significantly influenced by social status (p=0.032), but were not strongly influenced by LPS injection (p=0.086).

  • View in gallery

    (a) Predicted means and standard errors of aggression received by subordinate birds. Subordinate birds received significantly less aggression from mid-ranked birds but not dominant birds upon LPS treatment (p=0.0034). (b) Predicted means and standard errors of aggression initiated by dominant birds. Dominant house finches significantly reduced the amount of aggression they initiated upon LPS injection (p<0.001), regardless of flockmate identity.

Index Card

Content Metrics

Content Metrics

All Time Past Year Past 30 Days
Abstract Views 13 13 10
Full Text Views 10 10 10
PDF Downloads 2 2 2
EPUB Downloads 0 0 0