Save

Effects of food matrix on the prebiotic efficacy of inulin-type fructans: a randomised trial

In: Beneficial Microbes
Authors:
P.P.J. Jackson Department of Food and Nutritional Sciences, University of Reading, Harry Nursten Building, Pepper Lane, Whiteknights, Reading RG6 6DZ, United Kingdom

Search for other papers by P.P.J. Jackson in
Current site
Google Scholar
PubMed
Close
,
A. Wijeyesekera Department of Food and Nutritional Sciences, University of Reading, Harry Nursten Building, Pepper Lane, Whiteknights, Reading RG6 6DZ, United Kingdom

Search for other papers by A. Wijeyesekera in
Current site
Google Scholar
PubMed
Close
,
S. Theis BENEO-Institute, BENEO GmbH, Wormser Str. 11, 67283 Obrigheim, Germany

Search for other papers by S. Theis in
Current site
Google Scholar
PubMed
Close
,
J. Van Harsselaar BENEO-Institute, BENEO GmbH, Wormser Str. 11, 67283 Obrigheim, Germany

Search for other papers by J. Van Harsselaar in
Current site
Google Scholar
PubMed
Close
, and
R.A. Rastall Department of Food and Nutritional Sciences, University of Reading, Harry Nursten Building, Pepper Lane, Whiteknights, Reading RG6 6DZ, United Kingdom

Search for other papers by R.A. Rastall in
Current site
Google Scholar
PubMed
Close
https://orcid.org/0000-0003-1775-5226
Download Citation Get Permissions

Access options

Get access to the full article by using one of the access options below.

Institutional Login

Log in with Open Athens, Shibboleth, or your institutional credentials

Login via Institution

Purchase

Buy instant access (PDF download and unlimited online access):

$40.00

Abstract

Recently there is much debate in the scientific community over the impact of the food matrix on prebiotic efficacy of inulin-type fructans. Previous studies suggest that prebiotic selectivity of inulin-type fructans towards bifidobacteria is unaffected by the food matrix. Due to differences in study design, definitive conclusions cannot be drawn from these findings with any degree of certainty. In this randomised trial, we aimed to determine the effects that different food matrices had on the prebiotic efficacy of inulin-type fructans following a standardised 10-day, 4-arm, parallel, randomised protocol with inulin either in pure form or incorporated into shortbread biscuits, milk chocolate or a rice drink. Similar increases in Bifidobacterium counts were documented across all four interventions using both fluorescence in situ hybridisation (pure inulin: +0.63; shortbread: +0.59; milk chocolate: +0.65 and rice drink: +0.71 (log10 cells/g wet faeces) and 16S rRNA sequencing quantitative microbiome profiling data (pure inulin: +1.21 × 109; shortbread: +1.47 × 109; milk chocolate: +8.59 × 108 and rice drink: +1.04 × 109 (cells/g wet faeces) (all P 0.05). From these results, we can confirm that irrespective of the food matrix, the selectivity of inulin-type fructans towards Bifidobacterium is unaffected, yet the compositional make-up of the food matrix may have implications regarding wider changes in the microbiota.

Content Metrics

All Time Past Year Past 30 Days
Abstract Views 1165 1165 77
Full Text Views 16 16 3
PDF Views & Downloads 24 24 5