Oxycerina gen.n. (Stratiomyidae: Stratiomyinae), including three new species, O. hauseri sp.n., O. merzi sp.n. and O. sabaha sp.n., is described from the Oriental Region and compared with related genera of Stratiomyinae and Raphiocerinae. The monotypic genus Scapanocnema Enderlein, 1914 is considered to be a synonym of Odontomyia Meigen, 1803; S. spathulipes Enderlein, 1914 and O. latitibia Rozkošný & Kovac, 1994 are considered to be new synonyms of O. luteiceps de Meijere, 1911. Cyrtopus Bigot, 1883, is also proposed as a synonym of Odontomyia, resulting in new or resurrected combinations for the species O. fastuosa (Bigot, 1883), O. magnifica Lachaise & Lindner, 1973, and O. smaragdifera (Lindner, 1938). Timorimyia Frey, 1934 is proposed as a new synonym of Acanthasargus White, 1914, resulting in A. bidentatus (Frey, 1934), comb.n. A key to the genera of the Oriental Stratiomyinae and Raphiocerinae is presented.