Bernhard Sabel and ‘Residual Vision Activation Theory’: a History Spanning Three Decades

in Multisensory Research
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This review has the purpose of retracing the work of Professor Bernard Sabel and his group over the last 2–3 decades, in order to understand how they achieved formulation of the ‘Residual Vision Activation Theory’. The methodology proposed is described, from the first studies in 1995 with High Resolution Perimetry requiring a six-months training period, to the new technologies, such as repetitive transorbital Alternating Current Stimulation, that require ten days of training. Vision restoration therapy has shown improvement in visual responses irrespective of age at the training, lesion aetiology and site of lesion. The hypothesis that visual training may induce network plasticity, improving neuronal networks in cortical and subcortical areas of both hemispheres, appears to be confirmed by recent studies including observation of the cerebral activity by fMRI and EEG. However, the results are quite variable and the mechanisms that influence cerebral activity are still unclear. The residual vision activation theory has been much criticized, both for its methodology and analysis of the results, but it gave a new impulse to the research in this area, stimulating more studies on induced cerebral plasticity.

Bernhard Sabel and ‘Residual Vision Activation Theory’: a History Spanning Three Decades

in Multisensory Research

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Figures

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    Visual field size and training area. The first column shows the result of the perimetry, left and right eye were tested separately. Each circle represents the visual field of each eye up to 60° eccentricity, black indicates blind areas, shaded parts represent fields of inadequate vision and white sections represent intact areas. The second column displays the four possible monitor positions in relation to the visual field squares. The circle shows the binocular visual field, the small grey square is the area that was trained. The last column shows the result of the PERIMAT program in the trained area before and after training. Modified from Kasten and Sabel (1995).

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    Determination of the transition zone: superimposed data from 5 PeriMa tests. Black squares = stimulus positions with no response; grey squares = 1–4 responses; white squares = 5 responses. Modified from Kasten et al. (1998a).

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