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Translational biology of nematode effectors. Or, to put it another way, functional analysis of effectors – what’s the point?

In: Nematology
Authors:
Sophie Mantelin 1Dundee Effector Consortium, Cell and Molecular Sciences, The James Hutton Institute, Invergowrie, Dundee, DD2 5DA, UK

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Peter Thorpe 1Dundee Effector Consortium, Cell and Molecular Sciences, The James Hutton Institute, Invergowrie, Dundee, DD2 5DA, UK

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John T. Jones 1Dundee Effector Consortium, Cell and Molecular Sciences, The James Hutton Institute, Invergowrie, Dundee, DD2 5DA, UK
2Biology Department, University of St Andrews, St Andrews, Fife KY16 9TZ, UK

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There has been a huge amount of work put into identifying and characterising effectors from plant-parasitic nematodes in recent years. Although this work has provided insights into the mechanisms by which nematodes can infect plants, the potential translational outputs of much of this research are not always clear. This short article will summarise how developments in effector biology have allowed, or will allow, new control strategies to be developed, drawing on examples from nematology and from other pathosystems.

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