A new root-knot nematode parasitising coffee in the region of the Izalco volcano, Sansonate, El Salvador, is described as Meloidogyne izalcoensis n. sp. The suggested common name is El Salvador coffee root-knot nematode. The perineal pattern is characterised by the moderately high to high, squareish to rounded, dorsal arch, striae coarse, smooth to wavy, sometimes zigzaggy, usually without a distinct whorl, and similar to that of M. incognita and M. paranaensis. The female head region set off from body, sometimes annulated, and the labial disc has two prominent elevations or bumps on the ventral side that are slightly raised above the medial lips. The female stylet is robust, 15.0-16.0 μm long and with the DGO at 4.5-6.0 μm posterior to the knobs. Males have a high, round, head cap continuous with the body contour and the labial disc is fused with the medial lips to form an elongated structure. The head region is never marked by incomplete annulations. The stylet is robust, 23.0-26.0 μm long, and has rounded, backwardly sloping, knobs with the DGO located at 4.0-7.0 μm posteriorly. The stylet of second-stage juveniles is 12.0-13.0 μm long and the DGO is located 3.0-4.0 μm posterior to the stylet base; the tail is 45-48 μm long, conoid, with a rounded terminus. Biochemically, the esterase phenotype I4 (= Sa4) (Rm: 0.86, 0.96, 1.24, 1.30) is unique and is the most useful character to differentiate M. izalcoensis n. sp. from all other species.