Changes unleashed by liberalization and globalization acquire great significance in the context of India as a result of its economy formerly being inward-looking for decades. Here is a bird's eye view of certain trend developments in the technological regime in India that now characterize an outward-looking economy. Such changes are perceived as a threefold articulation: reorienting the industrial research laboratories, particularly the public-funded ones; reshaping technological research in academics; and adapting to competition through technological changes in industry, particularly in the manufacturing sector. The paper brings out the unfolding technological dynamism experienced by a developing economy, with its industrial capitalism only recently integrated through globalization. It shows how the technological regime is adapting to hard conditions via the emergence of globalization.