Aflatoxins and the traditional process of nixtamalisation in indigenous communities from the Huasteca Potosina region
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Aflatoxins represent one of the biggest public health problems in food safety, due to their toxic potential for humans and animals. They can lead to serious threats, such as hepatotoxicity, teratogenicity and immunotoxicity. Maize is the most important cereal consumed in Mexico, with which tortillas, tamales, flours, toasts and other products are elaborated. The elaboration of tortillas begins with nixtamalisation, which is an ancient maize process, developed and applied by indigenous Mesoamerican population. Some studies have shown the effect of nixtamalisation in the inactivation of aflatoxins. The purpose of this research was to record the traditional nixtamalisation process (TNP) and to register the presence of the aflatoxin B1 (AFB1) in tortillas and the exposure to AFB1 in indigenous communities living in the Huasteca Potosina, in central México. To register the nixtamalisation technique, a questionnaire was given to women, to illustrate the process step by step. Digestion, extraction, purification, and identification of the adduct AFB1-lysine (AFB1-Lys) in serum were performed. The TNP was analysed by 51 surveys, 4% of the tortillas was above the maximum permissible levels, according to Mexican guidelines; however, all blood samples showed presence of AFB1. TNP done in indigenous communities in the Huasteca Potosina region is not efficient enough to eliminate aflatoxins present in contaminated maize. It is necessary to improve conditions of places in which the grain is stored and knowledge about the risk of exposure to aflatoxins in rural communities, as key steps for preventing exposure to this type of mycotoxins.
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-
Adeyeye, S.A.O., 2016. Fungal mycotoxins in foods: a review. Cogent Food and Agriculture 2: 1213127.https://doi.org/10.1080/23311932.2016.1213127
-
Alberts, J.F., Gelderblom, W.C.A., Botha, A. and Van Zyl, W.H., 2009. Degradation of aflatoxin B1 by fungal laccase enzymes. International Journal of Food Microbiology 135: 47-52.https://doi.org/10.1016/j.ijfoodmicro.2009.07.022
-
Anguiano-Ruvalcaba, G.L., Vargas-Cortina, V.A. and Guzmán-De Peña, D., 2005. Inactivación de aflatoxina B1 y aflatoxicol pornixtamalización tradicional del maíz y su regeneración por acidificación de la masa. Salud Publica Mexico 47: 369-375.
'Inactivación de aflatoxina B1 y aflatoxicol pornixtamalización tradicional del maíz y su regeneración por acidificación de la masa ' () 47 Salud Publica Mexico : 369 -375.
-
Castañeda-Díaz de León, A., Aradillas-García, C. and Luevano-Contreras, C., 2018. Malnutrition and program coverage, a pilot study in indigenous Tenek children in Tocoy, Mexico. Salud Publica de México 60: 378-379.https://doi.org/10.21149/9108
-
Castañeda-Díaz de León, A., Aradillas-García, C., Luévano, C.C., Cilia, L.G. and Galván, A.G.J., 2015. Disponibilidad de alimentos de la canasta alimentaria rural en la comunidad indígena Tének de Tocoy en la Huasteca Potosina y comparación de costos con el área urbana de San Luis Potosí. Revista Española de Nutrición Comunitaria 21(4): 24-29.https://doi.org/10.14642/RENC.2015.21.4.5119
-
CEDRSSA, 2014. Consumo, distribución y producción de alimentos: el caso del complejo maíz-tortilla. LXII Legislatura. Cámara de Diputados.
-
Cheng, J., Fan, Y. and Zhao, L., 2016. Review on biological degradation of mycotoxins. Animal Nutrition 2: 127-133.https://doi.org/10.1016/j.aninu.2016.07.003
-
European Commission (EC), 2006. Commission Regulation (EC) No 1881/2006 of 19 December 2006 setting maximum levels for certain contaminants in foodstuffs. Official Journal of the European Union L 364: 5-24.
-
European Commission (EC), 2010. Commission Regulation (EU) No 165/2010 of 26 February 2010 amending Regulation (EC) No 1881/2006 setting maximum levels for certain contaminants in foodstuffs as regards aflatoxins. Official Journal of the European Union L 50: 8-12.
-
Dellafiora, L., Galaverna, G., Reverberi, M. and Dall’Asta, C., 2017. Degradation of aflatoxins by means of laccases fromTrametes versicolor: anin silico insight. Toxins 9: 1-17.https://doi.org/10.3390/toxins9010017
-
Díaz de León-Martínez, L., Díaz-Barriga, F., Barbier, O., Guzmán, P.D.L., Ortega-Romero, M., Pérez-Vázquez, F. and Flores-Ramírez, R., 2019. Evaluation of emerging biomarkers of renal damage and exposure to aflatoxin B1 in Mexican indigenous women: a pilot study. Environmental Science and Pollution Research 26: 12205-12216.https://doi.org/10.1007/s11356-019-04634-z
-
Díaz de León-Martínez, L., Solis-Mercado, J., Rodríguez-Aguilar, M., Díaz-Barriga, F., Guzmán Ortíz, D. and Flores-Ramírez, R., 2019b. Assessment of aflatoxin B1-lysine adduct in serum of infant population of the Huasteca Potosina, México: a pilot study. World Mycotoxin Journal 12: 421-429.https://doi.org/10.3920/WMJ2019.2457
-
Elias-Orozco, R., Castellanos-Nava, A., Gaytan-Martinez, M., Figueroa-Cardenas, J.D. and Loarca-Pina, G., 2002. Comparison of Gnixtamalization and extrusion processes for a reduction in aflatoxin content. Food Additives and Contaminants 19: 878-885.https://doi.org/10.1080/02652030210145054
-
García, S. and Heredia, N., 2006. Mycotoxins in Mexico: epidemiology, management, and control strategies. Mycopathologia 162: 255-264.https://doi.org/10.1007/s11046-006-0058-1
-
González-Martell, A.D., Cilia-López, V.G., Aradillas-García, C., Castañeda-Díaz de León, A., De la Cruz-Gutiérrez, A., Zúñiga-Bañuelos, J., García-Aguilar, N., González-Cortés, C., and Díaz Barriga-Martínez, F., 2019. La seguridad alimentaria y nutricional en una comunidad indígena de México. Revista Española de Nutrición Comunitaria 25(3): 3-9.
'La seguridad alimentaria y nutricional en una comunidad indígena de México ' () 25 Revista Española de Nutrición Comunitaria : 3 -9.
-
Guzmán-De-Peña, D., 2010.The destruction of aflatoxins in corn by ‘nixtamalización’. In: Rai, M. and Varma, A. (eds.) Mycotoxins in food, feed and bioweapons. Springer Verlag, Berlin Heidelberg, Germany, pp. 39-49.https://doi.org/10.1007/978-3-642-00725-5_3
-
Guzmán-De-Peña, D., Trudel, L. and Wogan, G.N., 1995. Corn ‘nixtamalizacion’ and the fate of radiolabelled aflatoxin B1 in the tortilla making process. Bulletin of Environmental Contamination and Toxicology 55: 858-864.https://doi.org/10.1007/bf00209465
-
International Agency for Research on Cancer (IARC), 2012. Aflatoxins. In: Chemical agents and related occupations. IARC Monographs on the evaluation of carcinogenic risks to humans. Vol. 100F. IARC, Lyon, France, pp. 226-248. Available at:http://tinyurl.com/ogoj86t.
-
Jager, A.V., Tonin, F.G., Baptista, G.Z., Souto, P.C.M.C. and Oliveira, C.A.F., 2016. Assessment of aflatoxin exposure using serum and urinary biomarkers in Sao Paulo, Brazil: a pilot study. International Journal of Hygiene and Environmental Health 219: 294-300.https://doi.org/10.1016/j.ijheh.2015.12.003
-
Karlovsky, P., Suman, M., Berthiller, F., De Meester, J., Eisenbrand, G., Perrin, I., Oswald, I.P., Speijers, G., Chiodini, A., Recker, T. and Dussort, P., 2016. Impact of food processing and detoxification treatments on mycotoxin contamination. Mycotoxin Research 32: 179-205.https://doi.org/10.1007/s12550-016-0257-7
-
Kensler, T.W., Roebuck, B.D., Wogan, G.N. and Groopman, J.D., 2011. Aflatoxin: a 50-year odyssey of mechanistic and translational toxicology. Toxicological Sciences 120, Suppl. 1: S28-S48.https://doi.org/10.1093/toxsci/kfq283
-
Leroy, J.L., Wang, J.S. and Jones, K., 2015. Serum aflatoxin B1-lysine adduct level in adult women from Eastern Province in Kenya depends on household socio-economic status: a cross sectional study. Social Science and Medicine 146: 104-110.https://doi.org/10.1016/j.socscimed.2015.10.039
-
Liu, Y. and Wu, F., 2010. Global burden of aflatoxin-induced hepatocellular carcinoma: a risk assessment. Environmental Health Perspectives 118: 818-824.https://doi.org/10.1289/ehp.0901388
-
Méndez-Albores, J.A., Arámbula-Villa, G., Loarca-Piña, M.G., González-Hernández, J., Castaño-Tostado, E. and Moreno-Martínez, E., 2004a. Aflatoxins’ fate during thenixtamalization of contaminated maize by two tortilla-making processes. Journal of Stored Products Research 40: 87-94.https://doi.org/10.1016/0022-474X(02)00080-2
-
Méndez-Albores, J.A., Villa, G.A., Del Rio-García, J.C. and Martínez, E.M., 2004b. Aflatoxin-detoxification achieved with Mexican traditionalnixtamalization process (MTNP) is reversible. Journal of the Science of Food and Agriculture 84: 1611-1614.https://doi.org/10.1002/jsfa.1853
-
Mexican Ministry of Health, 2002a. Norma Oficial Mexicana NOM-188-SSA12-002. Productos y Servicios. Control de aflatoxinas en cereales para consumo humano y animal. Especificaciones sanitarias. Información comercial. Métodos de prueba. Mexican Ministry of Health, Mexico.
-
Mexican Ministry of Health, 2002b. NOM-187-SSA1/SCFI-2002. Productos y servicios. Masa, tortillas, tostadas y harinas preparadas para su elaboración y establecimientos donde se procesan. Especificaciones sanitarias. Mexican Ministry of Health, Mexico.
-
Mexican Ministry of Health, 2013. Boletines de Información Estadística. Vol II. Daños a la salud. Mexican Ministry of Health, Mexico.
-
Miller, J.D., 2019. Mycotoxin contamination research. FST Magazine April 2019: 12-14.
'Mycotoxin contamination research ' () 2019 FST Magazine April : 12 -14.
-
Palencia, E., Torres, O., Hagler, W., Meredith, F.I., Williams, L.D. and Riley, R.T., 2003. Total fumonisins are reduced in tortillas using the traditionalnixtamalization method of Mayan communities. Journal of Nutrition 133: 3200-3203.https://doi.org/10.1093/jn/133.10.3200
-
Pons Jr, W.A., Cucullu, A.F., Franz Jr, A.O., 1972. Rapid quantitative TLC method for determining aflatoxins in cottonseed products. Journal of the Association of Official Analytical Chemists 55: 768-774.
'Rapid quantitative TLC method for determining aflatoxins in cottonseed products ' () 55 Journal of the Association of Official Analytical Chemists : 768 -774.
-
Qun-Ying, S., 2019. The toxification and detoxification mechanisms of aflatoxin B1 in human: an update. IntechOpen, London, UK.
'The toxification and detoxification mechanisms of aflatoxin B1 in human: an update', ().
-
Ramírez-Araujo, H., Gaytán-Martinez, M. and Reyes-Vega, M.L., 2019. Alternative technologies to the traditionalnixtamalization process: review. Trends in Food Science and Technology 85: 34-43.https://doi.org/10.1016/j.tifs.2018.12.007
-
Rangel-Meza, E., Muñoz, O., Vázquez-Carrillo, A., Cuevas-Sánchez, G., Merino-Castillo, J. and Miranda-Colín, S., 2004.Nixtamalización, elaboración y calidad de tortilla de maíces de Ecatitlán, Puebla, México. Agrocencia 38: 53-61.
'Nixtamalización, elaboración y calidad de tortilla de maíces de Ecatitlán, Puebla, México ' () 38 Agrocencia : 53 -61.
-
Roman, S., Fierro, N.A., Moreno-Luna, L.E. and Panduro, A., 2013. Hepatitis B virus genotype H and environmental factors associated to the low prevalence of hepatocellular carcinoma in Mexico. Journal of Cancer Therapy 4: 367-376.https://doi.org/10.4236/jct.2013.42A044
-
Rushing, B.R. and Selim, M.I., 2019. Aflatoxin B1: a review on metabolism, toxicity, occurrence in food, occupational exposure, and detoxification methods. Food and Chemical Toxicology 124: 81-100.https://doi.org/10.1016/j.fct.2018.11.047
-
Schaarschmidt, S. and Fauhl-Hassek, C., 2019. Mycotoxins during the processes ofnixtamalization and tortilla production. Toxins 11: 1-27.https://doi.org/10.3390/toxins11040227
-
Scholl, P.F. and Groopman, J.D., 2004. Synthesis of 5,5,6,6-D4-L-lysineaflatoxin Bl for use as a mass spectrometric internal standard. Journal of Labelled Compounds and Radiopharmaceuticals 47: 807-815.https://doi.org/10.1002/jlcr.867
-
Serna-Saldivar, S.O., 2016. History of corn and wheat tortillas. In: Rooney, L.W. and Serna-Saldivar, S.O. (eds.) Tortillas. AACC International Press, St. Paul, MN, USA, pp. 1-28.https://doi.org/10.1016/B978-1-891127-88-5.50001-3
-
Taniwaki, M.H., Pitt, J.I. and Magan, N., 2018.Aspergillus species and mycotoxins: occurrence and importance in major food commodities. Current Opinion in Food Science 23: 38-43.https://doi.org/10.1016/j.cofs.2018.05.008
-
Temba, B.A., Sultanbawa, Y., Kriticos, D.J., Fox, G.P., Harvey, J.J.W. and Fletcher, M.T., 2016. Tools for defusing a major global food and feed safety risk: nonbiological postharvest procedures to decontaminate mycotoxins in foods and feeds. Journal of Agriculture and Food Chemistry 64: 8959-8972.https://doi.org/10.1021/acs.jafc.6b03777
-
Tola, M. and Kebede, B., 2016. Occurrence, importance and control of mycotoxins: a review. Cogent Food and Agriculture 2: 1191103.https://doi.org/10.1080/23311932.2016.1191103
-
Torres, O., Matute, J., Gelineau-Van Waes, J., Maddox, J.R., Gregory, S.G., Ashley-Koch, A.E., Showker, J.L., Voss, K.A. and Riley, R.T., 2015. Human health implications from co-exposure to aflatoxins and fumonisins in maize-based foods in Latin America: Guatemala as a case study. World Mycotoxin Journal 8: 143-159.https://doi.org/10.3920/WMJ2014.1736
-
Torres, P., Guzmán-Ortiz, M. and Ramírez-Wong, B., 2001. Revising the role of pH and thermal treatments in aflatoxin content reduction during the tortilla and deep frying processes. Journal of Agriculture and Food Chemistry 49: 2825-2829.https://doi.org/10.1021/jf0007030
-
Villela-Castrejón, B., Acosta-Estrada, A. and Gutiérrez-Uribe, J.A., 2017. Microencapsulation of corn wastewater (nejayote) phytochemicals by spray drying and their release under simulated gastrointestinal digestion. Journal of Food Science 82: 1726-1734.https://doi.org/10.1111/1750-3841.13762
-
Voss, K.A., Poling, S.M., Meredith, F.I., Bacon, C.W. and Saunders, D.S., 2001. Fate of fumonisins during the production of fried tortilla chips. Journal of Agriculture and Food Chemistry 49: 3120-3126.https://doi.org/10.1021/jf001165u
-
Wild, C.P., Garner, R.C., Montesano, R. and Tursi, F., 1986. Aflatoxin-B1 binding to plasma-albumin and liver DNA upon chronic administration to rats. Carcinogenesis 7: 853-858.https://doi.org/10.1093/carcin/7.6.853
-
Yong-Kai, W., Xiao-Miao, Z., Meng-Meng, L., Jing-Xin, Y., Selvaraj, G., Yan-Fei, H., Guang-Fu, J. and Dong-Qing, W., 2018. Detoxification of aflatoxins on prospective approach: effect on structural, mechanical, and optical properties under pressures. Interdisciplinary Sciences: Computational Life Sciences 10: 311-319.https://doi.org/10.1007/s12539-017-0278-8
-
Zuki-Orozco, B.A., Batres-Esquivel, L.E., Ortiz-Pérez, M.D., Juárez-Flores, B.I. and Díaz-Barriga, F., 2018. Aflatoxins contamination in maize products from rural communities in San Luis Potosi, Mexico. Annals of Global Health 84: 300-305.https://doi.org/10.29024/aogh.918
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Aflatoxins and the traditional process of nixtamalisation in indigenous communities from the Huasteca Potosina region
In: World Mycotoxin JournalSearch for other papers by M. Rodríguez-Aguilar in
Current site
Google Scholar
PubMed
Search for other papers by J. Solís-Mercado in
Current site
Google Scholar
PubMed
Search for other papers by R. Flores-Ramírez in
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PubMed
Search for other papers by F. Díaz-Barriga in
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PubMed
Search for other papers by A. Zuki-Orozco in
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Search for other papers by V.G. Cilia-López in
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Aflatoxins represent one of the biggest public health problems in food safety, due to their toxic potential for humans and animals. They can lead to serious threats, such as hepatotoxicity, teratogenicity and immunotoxicity. Maize is the most important cereal consumed in Mexico, with which tortillas, tamales, flours, toasts and other products are elaborated. The elaboration of tortillas begins with nixtamalisation, which is an ancient maize process, developed and applied by indigenous Mesoamerican population. Some studies have shown the effect of nixtamalisation in the inactivation of aflatoxins. The purpose of this research was to record the traditional nixtamalisation process (TNP) and to register the presence of the aflatoxin B1 (AFB1) in tortillas and the exposure to AFB1 in indigenous communities living in the Huasteca Potosina, in central México. To register the nixtamalisation technique, a questionnaire was given to women, to illustrate the process step by step. Digestion, extraction, purification, and identification of the adduct AFB1-lysine (AFB1-Lys) in serum were performed. The TNP was analysed by 51 surveys, 4% of the tortillas was above the maximum permissible levels, according to Mexican guidelines; however, all blood samples showed presence of AFB1. TNP done in indigenous communities in the Huasteca Potosina region is not efficient enough to eliminate aflatoxins present in contaminated maize. It is necessary to improve conditions of places in which the grain is stored and knowledge about the risk of exposure to aflatoxins in rural communities, as key steps for preventing exposure to this type of mycotoxins.
| All Time | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 23 | 23 | 0 |
| Full Text Views | 21 | 20 | 0 |
| PDF Views & Downloads | 11 | 10 | 0 |