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Effect of gallic acid on Aspergillus carbonarius growth and ochratoxin A production

In: World Mycotoxin Journal
Authors:
S. Romero Laboratorio de Microbiología de Alimentos, Departamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, Pab. II, 3° Piso (1428), Buenos Aires, Argentina

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M. Alberto Facultad de Bioquímica Química y Farmacia, Universidad Nacional de Tucumán, Ayacucho 491 (4000), Tucumán, Argentina

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G. Vaamonde Laboratorio de Microbiología de Alimentos, Departamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, Pab. II, 3° Piso (1428), Buenos Aires, Argentina

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The aim of the present study was to investigate the gallic acid influence on Aspergillus carbonarius growth and ochratoxin A (OTA) biosynthesis. A mixed inoculum was used in Czapek Yeast Extract Agar and growth and OTA production was observed at 100 to 500 mg/l of the phenolic compound. Slower colony growth rates and longer lag phases were observed with increasing concentration and 500 mg/l was totally inhibitory for A. carbonarius growth. OTA production decrease was observed even at the lower concentration assayed. Gallic acid could be used as a natural antimicrobial for the control of ochratoxigenic A. carbonarius.

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