This chapter examines some of the literature regarding how arts-based methods are being employed in interdisciplinary contexts, including geography, health care humanities, women’s studies and aboriginal studies, among others. Here, the literature demonstrates that arts-based methods often reveal transformational results (Freire, 1970; Greene, 1995). At the same time, the literature shows that researchers outside of the arts who employ arts-based methods are often doing so to engage research participants and that many researchers feel uncertain about their abilities to conduct arts-based research (Jones, 2014). In other words, they are not making art themselves. This generates questions and points to a gap in the literature. What would transpire if more researchers outside of the arts had support to make art in, with and about their respective fields? With this query, I propose a call to action to work with researchers outside of the arts to open up spaces of arts-based possibilities. Opportunities to re-imagine approaches to knowing and coming to know are countless.