Bed bugs have long been associated with human habitation. They are not known to transmit disease, but their bites cause considerable nuisance, and may trigger allergic reactions in some people. Infestations in the hospitality industry have significant economic impact for those managing such premises. Bed bugs became much less common in developed countries during the period c. 1950–1990, but commencing in the late 1990’s, there was evidence of a substantial resurgence of the temperate bed bug (Cimex lectularius) in parts of Europe, the Americas, and Australia, coupled with increasing difficulty in controlling the infestations. The recent discovery of widespread resistance to some insecticides commonly used to control bed bugs is the most likely explanation for the increase, although other factors may also play a part. A variety of technologies have been developed to help control the resurgence, and Codes of Practice are being developed to standardise and improve control measures.