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  • Author or Editor: Dirk S. Schmeller x
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Itraconazole is the most widely used treatment against Batrachochytrium dendrobatidis (Bd), the fungal pathogen causing chytridiomycosis, a proximate cause of amphibian declines. Several side effects of itraconazole treatment, ranging in severity from depigmentation to death have been reported in different amphibian species and life stages, and these side effects were observed at commonly used dosages of itraconazole. However, no studies have investigated side-effects of itraconazole in conjunction with environmental stress. Post-metamorphic midwife toads (Alytes obstetricans) that were treated with itraconazole and subsequently exposed to a cold stress (exposure to 4°C cold water) had higher mortality rates compared to untreated individuals. Moreover, adults of booroolong frogs (Litoria booroolongensis) treated with itraconazole had a higher probability to become infected when subsequently exposed to Bd. Our results suggest that a post-metamorphosis itraconazole treatment of infected midwife toads combined with a subsequent release into the wild may be an ineffective disease mitigation strategy, as the cold stress during hibernation and/or exposure to Bd in the wild may reduce the hibernation emergence rate of treated individuals in this species.

In: Amphibia-Reptilia

Infectious diseases are considered as a significant factor in the global decline of amphibians. In some vertebrates, the assessment of the individual sexual traits can be useful for assessment of their health status and immunocompetence due to trade-off between them and investment in the immune system. Our aim here was to determine whether the trade-off between the expression of sexual morphological and behavioral traits and investment in the immune system is present in an urodele, the Palmate newt (Lissotriton helveticus). The groups of males were injected by solutions of proinflammatory agent, lipopolysaccharide (LPS) from Escherichia coli serotype O:55:B5, at dosages toxic to vertebrates (2 and 10 mg/kg of body mass) or by saline solution only (control groups). They were subsequently measured for variations in body condition and expression of both morphological (filament length, hind-foot-web, crest) and behavioral (courtship frequency) sexual traits. The injection of either LPS or saline solution did not cause any adverse effect on health in any male of all groups. No significant differences in any of the sexual traits were observed between two groups of males injected by LPS and control groups of males indicating the absence of a trade-off between immune response and expression of sexual traits. Our result suggests that measuring morphological or behavioral sexual traits may not be a useful method for monitoring emergence of infectious diseases in the palmate newt.

In: Amphibia-Reptilia

The emerging infectious disease chytridiomycosis is one of the major factors triggering global amphibian declines. A recently discovered species of chytrid fungus, Batrachochytrium salamandrivorans (Bsal), likely originated in East Asia, has led to massive declines in populations of fire salamanders (Salamandra salamandra) after its apparent introduction to the Netherlands and Belgium. Here, we report the first detection of this pathogen in Germany where it caused mass mortality of fire salamanders in a captive collection. Salamanders from this collection showed an almost 100% prevalence of infection with Bsal. Supposed Bsal-induced mortality occurred in multiple Salamandra species (S. salamandra, S. algira, S. corsica, and S. infraimmaculata), while Bsal infection was confirmed in nine subspecies of S. salamandra and in S. algira. Our study indicates that this pathogen can potentially infect all fire salamander species and subspecies. If Bsal spreads from captive collections to wild populations, then a similar devastating effect associated with high mortality should be expected.

In: Amphibia-Reptilia

Abstract

The infectious chytrid fungus Batrachochytrium salamandrivorans (Bsal) has been responsible for severe population declines of salamander populations in Europe. Serious population declines and loss of urodelan diversity may occur if appropriate action is not taken to mitigate against the further spread and impact of Bsal. We provide an overview of several potential mitigation methods, and describe their possible advantages and limitations. We conclude that long-term, context-dependent, multi-faceted approaches are needed to successfully mitigate adverse effects of Bsal, and that these approaches should be initiated pre-arrival of the pathogen. The establishment of ex situ assurance colonies, or management units, for species threatened with extinction, should be considered as soon as possible. While ex situ conservation and preventive measures aimed at improving biosecurity by limiting amphibian trade may be implemented quickly, major challenges that lie ahead are in designing in situ disease containment and mitigation post-arrival and in increasing public awareness.

Open Access
In: Amphibia-Reptilia