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Abstract

<title> SUMMARY </title>The project for the Brera Observatory, Milan, Italy, was started, from 1764, by R. Boscovich who sketched out the duties of the astronomers in a ' Piano per la Specola di Brera ', which was an ambitious project for the carrying out a new theoretical and observational astronomy.The Archives of the Observatory, which go from about 1760 to about 1950, have been put in order and have been transferred to rooms suitable for the custody of the documents and the consultation of them.Three main parts constitute the Archives: a) Scientific Correspondence, b) Administrative Archives, c) Astronomers's Material Collections. There are, moreover, a cartographic section and a section of photographic plates and photographs. In this paper the history of the events which determined the present-day configuration is described. A description of the consistency of the Archives is included.

In: Nuncius

Abstract

title RIASSUNTO /title Da ricerche in archivi a Milano e a ?CTRLerr type="1" mess="Doute Cars isoles avec recollage" ?Modena risulta che G. B. Amici forn due telescopi all'Osservatorio astronomico di Brera, uno nella primavera e l'altro nell'autunno del 1811. Specialmente interessante questo secondo telescopio, per via delle sue grandi dimensioni: 17 piedi (parigini) di distanza focale e 11 pollici di apertura. Tuttavia proprio le dimensioni impedirono la piena utilizzazione delle sue capacit, essendo negati all'Osservatorio milanese i finanziamenti necessari per la sua collocazione e per una montatura stabile e versatile. Nel 1839 il telescopio fu modificato da Amici, che ne ridusse la lunghezza a 12 piedi, ma dovettero trascorrere ancora quattro anni prima che esso fosse collocato in una apposita torretta. Tuttavia l'equipaggiamento ausiliario rimase insoddisfacente, e il telescopio non fu mai adeguatamente sfruttato.

In: Nuncius

Phenotyping behavioral and cognitive processes is a critical practice in mouse research and reliable phenotypic assessment is an essential component of building well-defined links between genes and behavioral/cognitive functions.

The success of behavioral screens in neurobehavioral mouse genetics depends on the identification of reliable, reproducible, and high-throughput behavioral/cognitive measures from individual animals irrespective of the differences in opinions regarding how to tackle phenotyping in different behavioral domains. Furthermore, reliable behavioral assays must be resistant to inevitable environmental differences across laboratories since protocols can be replicated but not all the environmental conditions.

Here we present a cross-laboratory study of interval timing behaviors in mice. Two classically used mouse inbred substrains, C57BL/6J and C57BL/6N, were studied over several days in home-cages containing automated testing apparatus. Remarkably, all timing measures in mouse performance showed a robust reproducibility across centers and even small differences between the two substrains were comparable across laboratories. Moreover, we have observed a consistent increase in error rate during the light phase of the light–dark cycle, which suggests that mouse performance during this phase is compromised by a possible sleep inertia-like effect. Overall, our study demonstrates that analysis of mouse timing behavior can lead to robust and reliable endophenotypes in mouse behavioral genetic studies.

In: Timing & Time Perception