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Alfons Rüsch, Jeffrey R. Holt, Ruth Anne Eatock and Melissa A. Vollrath

varying rates to step deflections of the hair bundles. We consider contributions of this adaptation process and of input resistance and membrane capacitance to the frequency dependence of the receptor potential. Whole- cell recordings of transduction current and receptor potential were made from hair

Krylov, Dick and Akoev

mammals or inadequate accuracy of our experiments. As known, the difference in slowly and rapidly adapting neurons is mainly deter- mined by the difference in the spike adaptation rather than generator mechanisms (Nakajima and Onodera, 1969). In other words, the marked differences in adaptation are

Alison Heald, Mark Suggs and Susan Schiffman

(protease inhibitors and nucleoside analogs) were investigated in a gerbil model. Electrophysiological recordings were obtained from the chorda tympani nerve after lingual application of HIV medications. The effect of adaptation of the tongue to HIV medications on other taste stimuli with salty, sweet, sour

Ai-Qing Zhu and Shin-Ichi Terashima

(RF) with a train of dis- charges. The naming of P and M neurons is historical and does not refer to different adaptation rates. The differences in the sensory and electrophysiological properties of P and M neurons have not been reported except in the lamprey. The purpose of this research is to

I. Thalmann, M. T. Henzl and R. Thalmann

absent from the stereocilia (Sakaguchi et al ., 1997), oncomodulin is unlikely to participate in mechanoelectric transduction. Given the very high levels of calmodulin in the stereocilia of both inner and outer hair cells (Pack and Slepecky, 1995), it is far more probable that the adaptation process in

Crnjar and A. Liscia P.Solari

.5 m M ) or W-7 (0.1 and 0.5 m M ). A total of 40– 91 chemosensilla, from 10– 15  ies, were tested with every solution. Stimuli were applied to the sensilla in a random sequence and a 3 min interval was allowed between consecutive stimulations in order to minimize adaptation phenomena. At the end of

Majone, A. Liscia P.Solari and Crnjar

minimize adaptation phenomena. Stimulation lasted 1–2 s and a 3 min interval was allowed between successive stimulations. At the end of each sequence, the initial stimulating solution was tested again: whenever signiŽ cant variations in responsiveness were found the experiment was discarded. BSA (fraction

Kay H. Steen, Peter W. Reeh and Dimitrios Stefanidis

conditions (Lindahl, 1961). In the rat skin – nerve preparation, a distinct subpopulation of polymodal nociceptors can be excited by acid (pH 6.1) for prolonged periods without signs of adaptation or tachyphylaxis. In addition, protons proved to sensitize nociceptors to punctuate mechanical stimulation