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Matthew Vangheel, Walter Traunspurger and Nicole Spann

present work, potential effects of TC on C. elegans cultured in two types of media were evaluated and compared with respect to alterations in growth, reproduction and the population growth rate, specifically, by establishing dose-response curves and assessing the interrelationship of these endpoints

Luis Patronelli, Mauricio Zamponi and Elvira González Olivera

upon the quartzitic outcrop ecosystem of Punta Cantera and the sandbar ecosystem of Santa Clara del Mar from Mar del Plata (Argentina). The isolated marginal sphincters were stimulated at increasing KCl concentrations and analysed as a dose-response curve expressed in tension in grams (gr: grams force

Wade C. Sherbrooke

and Evolutionary Biology, University of Arizona, Tucson, Arizona 85721, USA Abstract. Rapid color-change in three congeneric desert lizards of diverse size was studied and compared. Using in vitro skins, the highest % skin-darkening values (15-19%) of dose-response curves for α -melanophore

Howard Ohr, James Sims, J. Ole Becker, Chad Hutchinson and Milton McGiffen

of Botany and Plant Sciences; 2 Department of Plant Pathology; 3 Department of Nematology, University of California, Riverside, CA 92521, USA Accepted for publication: 23 November 1998 Summary – Sigmoidal dose-response curves were derived for Meloidogyne incognita , Tylenchulus semipenetrans , and


resulting in a higher maximal response than with the natural ligand. The maximal response of an occupation receptor to the natural ligand and to a ligand derivative are the same. Analysis of dose-response curves allows discrimination between these two recep- tors even if the response can only be recorded a

W.F. Hieb, E.L.R. Stokstad and Carole B. Pinnock

sterol greatly stimulates growth (Buecher, Hansen & Yarwood, 1971). Dose-response curves using growth rate k and logarithm of population size at day 8 as parameters Fig. 1. Growth response of C. briggsae in casein supplemented medium expressed as growth rate and population size at day 8. 4 are shown

Alison Heald, Mark Suggs and Susan Schiffman

: saquinavir (Invirase Ž ), ritonavir (Norvir Ž ) and indinavir (Crixivan Ž ). The nucleoside analogs tested were: lamivudine (Epivir Ž ), didanosine (Videx Ž ), zidovudine (Retrovir Ž ) and stavudine (Zerit Ž ). Dose–response curves for each drug in the chorda tympani nerve and the effect of each drug on

K.-H. Tomaschko, D. Bückmann and R. Guckler

with seawater after 96 Fig. 2. Dose-response curves of 20-hydroxyecdysone (20E) and 20-hydroxyecdysone 22- acetate (20E22Ac) in the oesophagus dilatation assay (see fig. 1). Reactions were scored cither 100% or 0%. The plottcd curves represent mean valucs; n: number of test using 50 animals. each

Y. Takei, M. Tierney, K. Ashida, K. Hamano and N. Hazon

- ing of the blood pressure through the arterial cannula. Dose-response curves from 0.001-1.0 nmol/kg dogfish Al and dog- fish All were established (fig. 1 ). Doses ranging from 0.01-1 mg/ 1 OOg of [Sarl-Val5-Ala8]-All had no effect on basal arterial blood pressure and did not block the increase in

Naresh K. Sangwan, O.P. Malik and Mangel S. Malik

enhanced activity. The f3-ketoaldehyde analogue 14 was more toxic than a-unsubstituted 0-diketones (15-17, 19). The dose response curves for the different compounds tested were almost parallel (Table I). DISCUSSION Compounds with an ester function bearing aryloxy moiety at a-position (Malik et al., 1989