Haematologia , Vol. 30, No. 3, pp. 203 – 207 (2000) Ó VSP 2000. Paper St 14 (DX S52) VNTR polymorphism in the Indian population and its application in carrier detection and prenatal diagnosis of haemophilia A families S. SHETTY, K. GHOSH and D. MOHANTY ∗ Institute of Immunohaematology (ICMR
Marek Kowalczyk, Andrzej Jakubczak, Beata Horecka, Magdalena Gryzińska and Grażyna Jeżewska-Witkowska
Domestication of dogs involved strong artificial selection. After their introduction into the human environment, dogs were exposed to factors that were not encountered in the wild. The skin and hair are barriers separating the organism from the environment, and melanin plays a significant role in their protective function. The study compared a fragment of the sequence of the DCT gene, which is involved in melanin synthesis, between two species: the dog, which is exposed to similar carcinogenic factors as humans, and the raccoon dog, a species related to the dog but less exposed to anthropogenic factors.
A fragment of the DCT gene 443 base pairs in length was obtained. Two genotypes were distinguished within the raccoon dog population, differing in one nucleotide in the intron sequence (145A>G). Between the DNA profile of the dog and the consensus sequence of the raccoon dog, 18 polymorphic sites were found – 15 in the intron sequence and 3 in the exon sequence. One change in the exon (191G>A) caused an amino acid change (2E>K). The loss of two binding sites for factor SOX10 and one for JUN-FOS was noted in the dog sequence.
On the basis of the sequence analysed, non-coding regions were found to be more susceptible to changes. Polymorphism in introns may affect the transcription profile of the DCT gene. The loss of binding sites for factors SOX10 and JUN-FOS in the dog may be an adaptive change to a different environment with respect to the raccoon dog.
Jorge Gutiérrez-Rodríguez, Elena G. Gonzalez and Íñigo Martínez-Solano
, codominant, non-coding genetic markers consisting of repeats of one to six base pairs with high levels of length polymorphism due to higher rates of mutation than other genomic regions. Because of their high variability and ease of genotyping they are widely used to address questions in Evolutionary and
Wing polymorphism in Dorypteryx domestica (Smithers) (Psocoptera: Psyllipsocidae) ZUZANA KU � EROVÁ New wing morphs of the synanthropic psocid Dorypteryx domestica are described, including wing morphology and body measurements. These forms are intermediate in wing length and other morphological
M.R. Chacon, T. Garate, R.M.E. Parkhouse and P.R. Burrows
differentiation of two of the M. incognita races. Keywords: Meloidogyne incognita, rDNA, polymorphism The genus Meloidogyne comprises a widely distributed group of plant-parasitic nematodes usually known as root-knot nematodes. Although there are approx- imately 60 described species of root-knot nematodes, most
Maria Ines Bonansea and Marcos Vaira
Introduction Amphibians display an extensive array of colour and patterning with widespread polymorphisms for which a variety of mechanisms have been proposed (Hoffman and Blouin, 2000 ). Knowledge of variation is of prime importance to understand the maintenance of polymorphism
S.-A. Bengtson and K.E. Erikstad
Wing polymorphism in Amara quenseli (Schönherr) (Coleoptera: Carabidae) in Iceland S.-A. BENGTSON and K. E. ERIKSTAD In Iceland the carabid beetle Amara quenseli (Schönherr) is polymorphic for wing length and fre- quencies of macropterous, brachypterous, and intermediate individuals were scored
Michelle. Mattern and Hans Van Gossum
© Koninklijke Brill NV, Leiden, 2008 DOI: 10.1163/157075608X328099 Animal Biology 58 (2008) 257–273 www.brill.nl/ab A phylogenetic perspective on absence and presence of a sex-limited polymorphism Hans Van Gossum 1 , * and Michelle. Y. Mattern 2 1 Evolutionary Ecology Group, University of
Goran Zivanovic, Conxita Arenas and Francesc Mestres
Anderson, A. R., Hoffmann, A. A., McKechnie, S. W., Umina, P. A., Weeks, A. R. 2005. The latitudinal cline in the In(3R) Payne inversion polymorphism has shifted in the last 20 years in Australian Drosophila melanogaster populations. Mol. Ecol. 14: 851-858. Ara�z, P. A., Mestres, F
Pablo J. Hidalgo-Fernández, Rafael Pérez-Vicente, José Maldonado M. and José L. Ubera-Jiménez
H. Vernet P. Gynodioecy and mitochondrial DNA polymorphism in natural populations of Beta vulgaris ssp maritima Genet. Sel.Evol. 1994 26 87s-101s Darwin C. The different forms of flowers on plants of the same species. John Murray London 1877 Dawson A.J. Jones V.P. Leaver C.J. The