Save

Xylo-oligosaccharides enhance the growth of bifidobacteria and Bifidobacterium lactis in a simulated colon model

In: Beneficial Microbes
Authors:
H. Mäkeläinen 1Health and Nutrition, Danisco Finland, Sokeritehtaantie 20, 02460 Kantvik, Finland
henna.makelainen@danisco.com

Search for other papers by H. Mäkeläinen in
Current site
Google Scholar
PubMed
Close
,
S. Forssten 1Health and Nutrition, Danisco Finland, Sokeritehtaantie 20, 02460 Kantvik, Finland

Search for other papers by S. Forssten in
Current site
Google Scholar
PubMed
Close
,
M. Saarinen 1Health and Nutrition, Danisco Finland, Sokeritehtaantie 20, 02460 Kantvik, Finland

Search for other papers by M. Saarinen in
Current site
Google Scholar
PubMed
Close
,
J. Stowell 2Sweeteners Division, Danisco Limited, 41-51 Brighton road, Redhill, Surrey RH1 6YS, United Kingdom

Search for other papers by J. Stowell in
Current site
Google Scholar
PubMed
Close
,
N. Rautonen 1Health and Nutrition, Danisco Finland, Sokeritehtaantie 20, 02460 Kantvik, Finland

Search for other papers by N. Rautonen in
Current site
Google Scholar
PubMed
Close
, and
A.C. Ouwehand 1Health and Nutrition, Danisco Finland, Sokeritehtaantie 20, 02460 Kantvik, Finland

Search for other papers by A.C. Ouwehand in
Current site
Google Scholar
PubMed
Close
Open Access

Abstract

A semi-continuous, anaerobic colon simulator, with four vessels mimicking the conditions of the human large intestine, was used to study the fermentation of xylo-oligosaccharides (XOS). Three XOS compounds and a xylan preparation were fermented for 48 hours by human colonic microbes. Fructo-oligosaccharides (FOS) were used as a prebiotic reference. As a result of the fermentation, the numbers of Bifidobacterium increased in all XOS and xylan simulations when compared to the growth observed in the baseline simulations, and increased levels of Bifidobacterium lactis were measured with the two XOS compounds that had larger distribution of the degree of polymerisation. Fermentation of XOS and xylan increased the microbial production of short chain fatty acids in the simulator vessels; especially the amounts of butyrate and acetate were increased. XOS was more efficient than FOS in increasing the numbers of B. lactis in the colonic model, whereas FOS increased the Bifidobacterium longum numbers more. The selective fermentation of XOS by B. lactis has been demonstrated in pure culture studies, and these results further indicate that the combination of B. lactis and XOS would form a successful, selective synbiotic combination.

Content Metrics

All Time Past 365 days Past 30 Days
Abstract Views 0 0 0
Full Text Views 205 204 34
PDF Views & Downloads 133 131 8