Save

The effect of wild blueberry (Vaccinium angustifolium) consumption on oxidative stress, inflammation, and DNA damage associated with exercise

In: Comparative Exercise Physiology
Authors:
T. Bloedon College of Education and Human Development, Department of Exercise Science and STEM Education, University of Maine, Lengyel Gym 124, Orono, ME 04469-5735, USA

Search for other papers by T. Bloedon in
Current site
Google Scholar
PubMed
Close
,
S. Vendrame School of Biomedical Sciences, Department of Food Science and Human Nutrition, University of Maine, 232 Hitchner Hall, Orono, ME 04469, USA

Search for other papers by S. Vendrame in
Current site
Google Scholar
PubMed
Close
,
J. Bolton University of Maine Cooperative Extension, University of Maine, 105 Nutting Hall, Orono, ME 04469, USA

Search for other papers by J. Bolton in
Current site
Google Scholar
PubMed
Close
,
R. Lehnhard College of Education and Human Development, Department of Exercise Science and STEM Education, University of Maine, Lengyel Gym 124, Orono, ME 04469-5735, USA

Search for other papers by R. Lehnhard in
Current site
Google Scholar
PubMed
Close
,
P. Riso University of Milan, DeFENS – Department of Food Environmental and Nutritional Sciences, Division of Human Nutrition, Via Celoria 2, 20133 Milan, Italy

Search for other papers by P. Riso in
Current site
Google Scholar
PubMed
Close
, and
D. Klimis-Zacas School of Biomedical Sciences, Department of Food Science and Human Nutrition, University of Maine, 232 Hitchner Hall, Orono, ME 04469, USA

Search for other papers by D. Klimis-Zacas in
Current site
Google Scholar
PubMed
Close
Download Citation Get Permissions

Access options

Get access to the full article by using one of the access options below.

Institutional Login

Log in with Open Athens, Shibboleth, or your institutional credentials

Login via Institution

Purchase

Buy instant access (PDF download and unlimited online access):

€38.50€35.00 excl. VAT

The present study examined the effect of wild blueberries on oxidative stress, the inflammatory response and DNA damage associated with exercise in untrained individuals. Ten sedentary males, aged 21-26 years, completed two single bouts of treadmill exercise at 70% of their VO2max. One bout occurred prior to, and one occurred following daily consumption of 300 g of wild blueberries for eight weeks. Blood samples were drawn during both exercise bouts and assayed for measures of oxidative stress (manganese-superoxide dismutase: Mn-SOD), inflammation (tumour necrosis factor-alpha: TNF-α and interleukin-6: IL-6) and DNA damage (comet assay). Blood samples were obtained immediately pre-exercise, and post exercise at 0, 30 and 60 min, and 3 and 6 h. A significant interaction between pre- and post-intervention over time was detected in plasma Mn-SOD concentration. Post hoc comparisons showed no significant differences between time points pre- and post-intervention, although plasma Mn-SOD concentration showed a moderate trend 30 min after exercise with wild blueberry consumption (P=0.072). A significant increase in IL-6 was observed for time (at 30 min and 1 h) following exercise, both pre- and post-intervention. No significant differences were seen in DNA damage or TNF-α either with exercise or the intervention. This study demonstrates that a single bout of exercise at 70% of VO2max is sufficient to cause a significant increase in inflammation in untrained individuals. The trend for Mn-SOD concentration to decrease after exercise post-intervention indicates a potential benefit of wild blueberries to increase antioxidant capacity and reduce oxidative stress.

Content Metrics

All Time Past 365 days Past 30 Days
Abstract Views 173 110 20
Full Text Views 29 16 2
PDF Views & Downloads 18 7 1